Kalamazoo College is a member of the Great Lakes Colleges Association (GLCA), an association of 13 private liberal arts colleges in Michigan, Indiana, Ohio and Pennsylvania. The member colleges—Albion, Allegheny, Antioch, Denison, DePauw, Earlham, Hope, Kalamazoo, Kenyon, Oberlin, Ohio Wesleyan, Wabash, and Wooster—share facilities and resources in order to provide programs that no single college could undertake by itself.

Kalamazoo College students who meet appropriate qualifications are eligible to apply for participation in a fine arts program in New York City, a fall quarter seminar at the Newberry Library in Chicago, an urban studies program at The Philadelphia Center, a semester program on the U.S.-Mexico border through the Border Studies Program, and a science/social science term at the Oak Ridge National Laboratory in Tennessee. College faculty members serve as liaison advisers to these programs. Students interested in the GLCA programs should consult with the appropriate faculty advisor.